Hi ewn5711,
What information do you think is missing?
Some users have high pending messages could due to a number of reasons, e.g. your database is full (could affect the above issue as well), users are out of coverage, corrupted service books, users have been migrated to another mailbox or exchange server. As you can see it is pretty hard to blind troubleshoot.
Are you able to be more specific and provide more mail server and bes environment details? Most importantly, any error in the app log and have you assigned correct permission for your bes admin?
See http://www.blackberry.com/btsc/microsites/search.do?cmd=displayKC&docType=kc&externalId=KB02276
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If you issue is resolved, mark Accept Solution next to the resolution post.
Feel free to search www.blackberry.com/btsc to find your answers.
