That's a new one!! Most folks cannot figure out how to get into Safe Mode! Have you removed the battery for a reboot? Or just selecting the on-screen reboot item? If the latter, then please do try removing the battery for a good reboot.
It may also be that your ESC key is stuck...see if you can press/release it a few times (with the battery out, I'd suggest) and see if it will unstick.
Occam's Razor nearly always applies when troubleshooting technology issues!
If anyone has been helpful to you, please show your appreciation by clicking the button inside of their post. Please click here and read, along with the threads to which it links, for helpful information to guide you as you proceed. I always recommend that you treat your BlackBerry like any other computing device, including using a regular backup schedule...click here for an article with instructions.