Hello jjlangdon,
Yes, you can do a one way sync from your Mac to overwrite your BlackBerry data.
In the BlackBerry Desktop Manager, under the Calendar settings you will see an "Advanced Settings" at the bottom. When you expand this section, you can chose the date range of appointments to sync as well as there is a box to check off to say "Replace all calendar events on this BlackBerry device."
-HMthePirate
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